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Texans move on from Kenneth Murray, AFC South roundup

The Houston Texans parted ways with practice-squad linebacker Kenneth Murray heading into Week 6, as the AFC South lines up for a key Texans-Jaguars clash.

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By the PickALeague Newsroom · Published · Source: PickALeagueSummary written with AI assistance — how we workLire en français →

There were no games on the AFC South slate yesterday, but the practice squad churn in Houston, a major quarterback health story tied to Jacksonville, and an upset watch involving Indianapolis and Tennessee still gave the division plenty of intrigue heading into Week 6.

Houston Texans: Murray out, Braswell in on practice squad

Per Pro Football Rumors, the Houston Texans reshuffled their practice squad on Thursday ahead of their Week 6 showdown with the Jacksonville Jaguars. The 1-4 Texans signed defensive end Chris Braswell and released linebacker Kenneth Murray, removing Murray from the organization for now and ruling him out of this weekend’s divisional matchup against Jacksonville.

The move underscores Houston’s search for the right defensive mix as it tries to climb back into the AFC South race against the current division leader.

Jacksonville Jaguars: Hurts’ blood clot situation traces back to Jags game

The Jacksonville Jaguars (4-1) were idle yesterday, but they’re connected to one of the week’s biggest league-wide stories. CBS Sports reports that Philadelphia Eagles quarterback Jalen Hurts is sidelined indefinitely after a follow-up ultrasound detected movement in a superficial blood clot. Hurts initially played through the clot in a game against the Jaguars before being shut down.

While the development primarily impacts Philadelphia, it places the earlier interconference meeting with Jacksonville in a harsher light in terms of physical toll.

Indianapolis Colts vs. Tennessee Titans: upset alert in Week 6

On the prediction front, CBS Sports highlights the Week 6 AFC South clash between the Indianapolis Colts and Tennessee Titans as one of its top upset-alert games. The 2-3 Colts are described as touchdown favorites, yet the analysis suggests Indianapolis is not only at risk of failing to cover, but could lose outright to its 0-5 divisional rival.

For Tennessee, still searching for its first win of 2026, this is a chance to reset a bleak start. For Indianapolis, a stumble against a winless opponent would be a major setback in a division where the Jaguars have already opened an early lead.

Source: PickALeague.

This article is an original synthesis and analysis by PickALeague based on reporting from the source credited above. AI tools assisted with drafting and editing.