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49ers projected for deep playoff run — NFC West roundup

At 5-0, the 49ers are drawing optimistic playoff simulations, while the Cardinals and Rams tweak their depth charts and the Seahawks eye Thursday night.

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By the PickALeague Newsroom · Published · Source: PickALeagueSummary written with AI assistance — how we workLire en français →

There were no NFC West games on the schedule, but the division still generated storylines. The 5-0 San Francisco 49ers continue to headline league-wide projections, while the Arizona Cardinals and Los Angeles Rams made roster tweaks and the Seattle Seahawks popped up in prime-time picks.

49ers (5-0): simulations point to a long January

With Week 6 on deck, CBS Sports ran a simulation of the NFL’s remaining 193 games and projected the 49ers to make a deep playoff run. The outlet notes that San Francisco will "like" how the season plays out in that scenario, which matches the reality of a 5-0 start and first place in the NFC West.

Cardinals (1-4): Marvin Harrison Jr. saga dissected

The fallout from Marvin Harrison Jr.’s departure from Arizona remains a talking point. Pro Football Rumors revisited what it describes as a bizarre weekend, in which reports surfaced that the wide receiver was on the verge of being traded to an undisclosed team before the Houston Texans ultimately emerged as the 0-4 buyer. The site notes that Houston had to keep quiet about the pending move and connects the situation to Harrison signing with an agency this season, a factor that played into the Cardinals trading him away. Harrison has since passed his physical with the Texans.

On the personnel front, the 1-4 Cardinals are getting some reinforcements back and promoting from within. According to Pro Football Rumors, Arizona has designated safety Kitan Crawford for return from injured reserve and signed tight end Shawn Bowman to the active roster from the practice squad.

Rams (2-3): linebacker shuffle and a closer look at OT loss

The Rams, sitting at 2-3, shuffled their linebacker depth. Per Pro Football Rumors, they signed Garrett Nelson to the practice squad and released fellow linebacker Jamie Sheriff. The moves come on the heels of an overtime loss to the Buffalo Bills.

CBS Sports reports that Bills head coach Joe Brady admitted to a clock-management mistake in that game. Brady said Buffalo could have taken two knees before Tyler Bass’ game-winning field goal, which would have further limited the Rams’ chances to respond if the kick had missed.

Seahawks (3-2): backing from the picks column

In Seattle, attention turns to Thursday night. In his Week 6 predictions for CBS Sports, Pete Prisco is taking the 3-2 Seahawks over the Denver Broncos. With San Francisco setting the pace in the NFC West, Seattle stays firmly in the broader conversation thanks to projections like these, even on a quiet day without on-field action.

Source: PickALeague.

This article is an original synthesis and analysis by PickALeague based on reporting from the source credited above. AI tools assisted with drafting and editing.