Arizona Cardinals vs. San Francisco 49ers: game summary
Final · September 21, 2025 at 4:25 p.m.
Levi's Stadium
Summary
| Team |
|---|
Team stats
ARISF 
- 260Total yards355
- 154Passing yards282
- 22/35Completions/attempts27/41
- 4.3Yards per pass6.7
- 106Rushing yards73
- 28Rushing attempts20
- 3.8Yards per rush3.7
- 16First downs19
- 5-153rd down efficiency2-10
- 2-24th down efficiency1-2
- 1-3Red zone (made-att)1-4
- 64Total plays62
- 4.1Yards per play5.7
- 0Turnovers1
- 0Fumbles lost0
- 0Interceptions thrown1
- 1-5Sacks (yards lost)1-2
- 5-30Penalties (yards)5-69
- 34:39Time of possession25:21
Game leaders
Passing
Kyler MurrayARI · QB · 22/35, 159 YDS, 1 TD
Mac JonesSF · QB · 27/41, 284 YDS, 1 TD, 1 INT
Rushing
Trey BensonARI · RB · 10 CAR, 42 YDS
Christian McCaffreySF · RB · 17 CAR, 52 YDS
Receiving
Marvin Harrison Jr.ARI · WR · 3 REC, 44 YDS
Ricky PearsallSF · WR · 8 REC, 117 YDS
Scoring summary
2nd quarter
- Field goal8:45Chad Ryland 34 Yd Field Goal3-0
- Field goal4:22Eddy Pineiro 38 Yd Field Goal3-3
- Field goal0:17Eddy Pineiro 51 Yd Field Goal3-6
3rd quarter
- Field goal6:37Chad Ryland 28 Yd Field Goal6-6
4th quarter
- Touchdown10:50Kyle Juszczyk 1 Yd pass from Mac Jones (Eddy Pineiro Kick)6-13
- Touchdown8:37Trey McBride 1 Yd pass from Kyler Murray (Chad Ryland Kick)13-13
- Safety3:15Defensive Holding in Endzone for Safety15-13
- Field goal0:00Eddy Pineiro 35 Yd Field Goal15-16
Player stats
Arizona Cardinals
| Passing | C/ATT | YDS | AVG | TD | INT | SACKS | RTG |
|---|---|---|---|---|---|---|---|
| Kyler Murray | 22/35 | 159 | 4.5 | 1 | 0 | 1-5 | 82.9 |
| Rushing | CAR | YDS | AVG | TD | LONG |
|---|---|---|---|---|---|
| Trey Benson | 10 | 42 | 4.2 | 0 | 29 |
| Kyler Murray | 6 | 37 | 6.2 | 0 | 9 |
| James Conner | 9 | 22 | 2.4 | 0 | 9 |
| Greg Dortch | 1 | 5 | 5.0 | 0 | 5 |
| Emari Demercado | 2 | 0 | 0.0 | 0 | 1 |
| Receiving | REC | YDS | AVG | TD | LONG | TGTS |
|---|---|---|---|---|---|---|
| Marvin Harrison Jr. | 3 | 44 | 14.7 | 0 | 32 | 6 |
| Trey McBride | 5 | 43 | 8.6 | 1 | 17 | 8 |
| Zay Jones | 2 | 25 | 12.5 | 0 | 18 | 3 |
| James Conner | 3 | 15 | 5.0 | 0 | 10 | 4 |
| Trey Benson | 3 | 9 | 3.0 | 0 | 5 | 4 |
| Tip Reiman | 2 | 8 | 4.0 | 0 | 6 | 3 |
| Elijah Higgins | 1 | 7 | 7.0 | 0 | 7 | 1 |
| Michael Wilson | 1 | 5 | 5.0 | 0 | 5 | 2 |
| Greg Dortch | 2 | 3 | 1.5 | 0 | 2 | 2 |
| Emari Demercado | 0 | 0 | 0.0 | 0 | 0 | 1 |
| Defense | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
|---|---|---|---|---|---|---|---|
| Mack Wilson Sr. | 12 | 6 | 0 | 1 | 2 | 0 | 0 |
| Akeem Davis-Gaither | 8 | 5 | 0 | 0 | 0 | 0 | 0 |
| Jalen Thompson | 6 | 4 | 0 | 0 | 0 | 0 | 0 |
| Budda Baker | 6 | 3 | 0 | 0 | 0 | 0 | 0 |
| Kei'Trel Clark | 5 | 3 | 0 | 0 | 0 | 0 | 0 |
| Dadrion Taylor-Demerson | 4 | 4 | 0 | 0 | 1 | 0 | 0 |
| Dalvin Tomlinson | 3 | 3 | 0 | 1 | 0 | 1 | 0 |
| Max Melton | 3 | 2 | 0 | 0 | 0 | 0 | 0 |
| Denzel Burke | 2 | 2 | 0 | 0 | 0 | 0 | 0 |
| Josh Sweat | 2 | 1 | 1 | 1 | 0 | 2 | 0 |
| Kitan Crawford | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Zaven Collins | 2 | 0 | 0 | 0 | 0 | 1 | 0 |
| Cody Simon | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Calais Campbell | 1 | 1 | 0 | 0 | 0 | 3 | 0 |
| Simi Fehoko | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| PJ Mustipher | 1 | 1 | 0 | 0 | 1 | 0 | 0 |
| Jordan Burch | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Darius Robinson | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Baron Browning | 1 | 0 | 0 | 0 | 0 | 1 | 0 |
| Dante Stills | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Anthony Goodlow | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Owen Pappoe | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
San Francisco 49ers
| Passing | C/ATT | YDS | AVG | TD | INT | SACKS | RTG |
|---|---|---|---|---|---|---|---|
| Mac Jones | 27/41 | 284 | 6.9 | 1 | 1 | 1-2 | 83.8 |
| Rushing | CAR | YDS | AVG | TD | LONG |
|---|---|---|---|---|---|
| Christian McCaffrey | 17 | 52 | 3.1 | 0 | 15 |
| Brian Robinson Jr. | 2 | 22 | 11.0 | 0 | 19 |
| Mac Jones | 1 | -1 | -1.0 | 0 | -1 |
| Receiving | REC | YDS | AVG | TD | LONG | TGTS |
|---|---|---|---|---|---|---|
| Ricky Pearsall | 8 | 117 | 14.6 | 0 | 34 | 11 |
| Christian McCaffrey | 10 | 88 | 8.8 | 0 | 20 | 15 |
| Kendrick Bourne | 4 | 38 | 9.5 | 0 | 11 | 6 |
| Jake Tonges | 2 | 21 | 10.5 | 0 | 11 | 3 |
| Skyy Moore | 1 | 10 | 10.0 | 0 | 10 | 1 |
| Marquez Valdes-Scantling | 1 | 9 | 9.0 | 0 | 9 | 1 |
| Kyle Juszczyk | 1 | 1 | 1.0 | 1 | 1 | 1 |
| Defense | TOT | SOLO | SACKS | TFL | PD | QB HTS | TD |
|---|---|---|---|---|---|---|---|
| Fred Warner | 11 | 5 | 0 | 0 | 2 | 0 | 0 |
| Dee Winters | 8 | 4 | 0 | 0 | 1 | 1 | 0 |
| Sam Okuayinonu | 7 | 2 | 0 | 0 | 0 | 0 | 0 |
| Marques Sigle | 7 | 2 | 0 | 0 | 0 | 0 | 0 |
| Upton Stout | 5 | 3 | 0 | 0 | 1 | 0 | 0 |
| Bryce Huff | 5 | 2 | 1 | 1 | 1 | 2 | 0 |
| Ji'Ayir Brown | 4 | 2 | 0 | 0 | 0 | 0 | 0 |
| Renardo Green | 4 | 1 | 0 | 0 | 0 | 0 | 0 |
| Jason Pinnock | 3 | 3 | 0 | 0 | 0 | 0 | 0 |
| Deommodore Lenoir | 3 | 3 | 0 | 1 | 0 | 0 | 0 |
| Jordan Elliott | 3 | 1 | 0 | 1 | 0 | 0 | 0 |
| Mykel Williams | 2 | 2 | 0 | 1 | 0 | 1 | 0 |
| C.J. West | 2 | 1 | 0 | 0 | 0 | 0 | 0 |
| Luke Gifford | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Nick Bosa | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Kalia Davis | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Darrell Luter Jr. | 2 | 0 | 0 | 0 | 0 | 0 | 0 |
| Trent Williams | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Chase Lucas | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Tatum Bethune | 1 | 1 | 0 | 0 | 0 | 0 | 0 |
| Siran Neal | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
| Brayden Willis | 1 | 0 | 0 | 0 | 0 | 0 | 0 |
Game info
- Stadium
- Levi's Stadium · Santa Clara, CA
- Surface
- Natural grass
- Attendance
- 70,414
- TV
- Fox
- Officials
- Carl Johnson (Line judge) · John Hussey (Referee) · Allen Baynes (Side judge) · Max Causey (Down judge) · Matt Edwards (Back judge) · Anthony Flemming (Field judge) · Duane Heydt (Umpire)
About this game
Who won Cardinals vs 49ers?
49ers won 16-15 over Cardinals on Sunday, September 21, 2025.
When was Cardinals vs 49ers played?
On Sunday, September 21, 2025, at 4:25 PM ET at Levi's Stadium.
Where was Cardinals vs 49ers played?
At Levi's Stadium.